Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.44 |
| ▸ | PPARA | Q07869 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9613850 | 0.85 | PPARG (0.45) | PPARGPPARAMEN1KMT2AHTT | |
| SCHEMBL9614112 | 0.84 | PPARA (0.48) | PPARGPPARAMEN1KMT2AHTT | |
| SCHEMBL9614107 | 0.84 | PPARA (0.48) | PPARGPPARAMEN1KMT2AHTT | |
| SCHEMBL9858450 | 0.84 | PPARA (0.48) | PPARGPPARAMEN1KMT2AHTT | |
| SCHEMBL9858299 | 0.83 | PPARG (0.50) | PPARGPPARA | |
| SCHEMBL9614023 | 0.80 | PPARA (0.47) | PPARGPPARAMMP2MMP9 | |
| SCHEMBL9614046 | 0.80 | PPARA (0.48) | PPARGPPARAMEN1KMT2AHTT | |
| SCHEMBL9613899 | 0.79 | TAAR1 (0.47) | PPARGPPARAMEN1KMT2A | |
| SCHEMBL27274785 | 0.78 | PPARA (0.47) | PPARGPPARAMMP2MMP9 | |
| SCHEMBL9614490 | 0.78 | PPARA (0.53) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145611-A | Diabetes | BOEHRINGER MANNHEIM GMBH (DE) | 1992-09-08 | — | — | US | disclosed |
| EP-0279162-B1 | CARBONIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1991-06-19 | — | — | EP | disclosed |
| EP-0279162-A1 | Carbonic acid derivatives, process for their preparation and pharmaceuticals containing them | Roche Diagnostics GmbH (DE) | 1988-08-24 | — | — | EP | disclosed |