Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.45 |
| ▸ | PPARA | Q07869 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.37 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.37 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.37 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9614321 | 0.92 | CA2 (0.41) | PPARGPPARAMMP8MMP13 | |
| SCHEMBL9613841 | 0.91 | PPARG (0.43) | PPARGPPARAMEN1KMT2AHTT | |
| SCHEMBL9613899 | 0.89 | TAAR1 (0.47) | PPARGPPARAMEN1KMT2AADAMTS5 | |
| SCHEMBL9614103 | 0.85 | PPARG (0.44) | PPARGPPARAMEN1KMT2AHTT | |
| SCHEMBL9613878 | 0.84 | PPARA (0.47) | PPARGPPARAMEN1KMT2AMMP2 | |
| SCHEMBL9858450 | 0.82 | PPARA (0.48) | PPARGPPARAMEN1KMT2AHTT | |
| SCHEMBL9614112 | 0.82 | PPARA (0.48) | PPARGPPARAMEN1KMT2AHTT | |
| SCHEMBL9614107 | 0.82 | PPARA (0.48) | PPARGPPARAMEN1KMT2AHTT | |
| SCHEMBL9613989 | 0.82 | PPARA (0.43) | PPARGPPARAMMP2LMNAMAPT | |
| SCHEMBL9858299 | 0.81 | PPARG (0.50) | PPARGPPARAMMP3ADAMTS5TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145611-A | Diabetes | BOEHRINGER MANNHEIM GMBH (DE) | 1992-09-08 | — | — | US | disclosed |