Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858293 | 0.92 | FFAR1 (0.47) | PPARGTAAR1PTGESFFAR1ITGB3 | |
| SCHEMBL9613899 | 0.89 | TAAR1 (0.47) | PPARGPPARATAAR1PTGESFFAR1 | |
| SCHEMBL9614112 | 0.85 | PPARA (0.48) | PPARGPPARAALDH1A1 | |
| SCHEMBL9614107 | 0.85 | PPARA (0.48) | PPARGPPARAALDH1A1 | |
| SCHEMBL9858450 | 0.85 | PPARA (0.48) | PPARGPPARAALDH1A1 | |
| SCHEMBL9614490 | 0.83 | PPARA (0.53) | PPARGPPARA | |
| SCHEMBL9614103 | 0.83 | PPARG (0.44) | PPARGPPARA | |
| SCHEMBL9614023 | 0.81 | PPARA (0.47) | PPARGPPARA | |
| SCHEMBL9613850 | 0.81 | PPARG (0.45) | PPARGPPARATAAR1MMP3ADAMTS5 | |
| SCHEMBL9614046 | 0.81 | PPARA (0.48) | PPARGPPARAALDH1A1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279162-B1 | CARBONIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1991-06-19 | — | — | EP | disclosed |
| EP-0279162-A1 | Carbonic acid derivatives, process for their preparation and pharmaceuticals containing them | Roche Diagnostics GmbH (DE) | 1988-08-24 | — | — | EP | disclosed |