Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | EBP | Q15125 | 1/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2920196 | 0.82 | CYP2D6 (0.38) | PLA2G2APLA2G10PLA2G1BPLA2G5TDP1 | |
| SCHEMBL10929242 | 0.81 | PLA2G2A (0.45) | PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL9614104 | 0.81 | HDAC6 (0.39) | PLA2G2APLA2G10PLA2G1BPLA2G5HDAC6 | |
| SCHEMBL9613862 | 0.80 | ABCB1 (0.41) | HDAC6SIGMAR1EBPGGPS1 | |
| SCHEMBL9614038 | 0.80 | HDAC6 (0.40) | PLA2G2APLA2G10PLA2G1BPLA2G5HDAC6 | |
| SCHEMBL9614106 | 0.79 | HDAC6 (0.39) | PLA2G2APLA2G10PLA2G1BPLA2G5HDAC6 | |
| SCHEMBL9614110 | 0.76 | PLA2G2A (0.37) | PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL10551620 | 0.75 | PLA2G2A (0.39) | PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL909696 | 0.72 | CA1 (0.38) | — | |
| SCHEMBL10881889 | 0.72 | PLA2G2A (0.45) | PLA2G2APLA2G10PLA2G1BPLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116992-A | Antitumor | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1992-05-26 | — | — | US | disclosed |