Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.37 |
| ▸ | EBP | Q15125 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9614106 | 0.91 | HDAC6 (0.39) | HDAC6PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL9614104 | 0.87 | HDAC6 (0.39) | HDAC6PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL9575720 | 0.83 | PLA2G2A (0.43) | PLA2G2APLA2G10PLA2G1BPLA2G5NPC1 | |
| SCHEMBL9671339 | 0.80 | TLR2 (0.39) | HDAC6PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL9614113 | 0.80 | PLA2G2A (0.38) | HDAC6PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL9613862 | 0.80 | ABCB1 (0.41) | HDAC6EBPSIGMAR1GGPS1CTSK | |
| SCHEMBL9669469 | 0.79 | HDAC6 (0.41) | HDAC6 | |
| SCHEMBL9613936 | 0.76 | GGPS1 (0.44) | GGPS1 | |
| SCHEMBL10940286 | 0.73 | ALDH1A1 (0.41) | HDAC6PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL10833241 | 0.72 | PLA2G2A (0.43) | HDAC6PLA2G2APLA2G10PLA2G1BPLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116992-A | Antitumor | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1992-05-26 | — | — | US | disclosed |