Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | CTSG | P08311 | 2/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.34 |
| ▸ | CMA1 | P23946 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.33 |
| ▸ | TLR2 | O60603 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9613857 | 0.80 | MEN1 (0.45) | ADRB2ALDH1A1ADRB3 | |
| SCHEMBL10929242 | 0.80 | PLA2G2A (0.45) | PLA2G2APLA2G10PLA2G1BPLA2G5TLR2 | |
| SCHEMBL9614113 | 0.76 | PLA2G2A (0.38) | PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL10551620 | 0.73 | PLA2G2A (0.39) | PLA2G2APLA2G10PLA2G1BPLA2G5ALDH1A1 | |
| SCHEMBL909696 | 0.73 | CA1 (0.38) | MMP2MMP3 | |
| SCHEMBL10796999 | 0.72 | PLA2G2A (0.43) | PLA2G2APLA2G10PLA2G1BPLA2G5PRSS1 | |
| SCHEMBL10933731 | 0.72 | PLA2G2A (0.43) | PLA2G2APLA2G10PLA2G1BPLA2G5PRSS1 | |
| SCHEMBL14856058 | 0.72 | KIF11 (0.41) | ALDH1A1 | |
| SCHEMBL17443045 | 0.72 | KIF11 (0.41) | ALDH1A1 | |
| SCHEMBL14856176 | 0.72 | KIF11 (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116992-A | Antitumor | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1992-05-26 | — | — | US | disclosed |