Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.56 |
| ▸ | PPARA | Q07869 | 17/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696941 | 0.85 | PPARG (0.48) | PPARGPPARAFOLH1MTNR1AMTNR1B | |
| SCHEMBL9613979 | 0.83 | PPARG (0.63) | PPARGPPARAFOLH1CTRC | |
| SCHEMBL9614339 | 0.83 | PPARA (0.68) | PPARGPPARA | |
| SCHEMBL9614177 | 0.82 | PPARG (0.61) | PPARGPPARAFOLH1CTRC | |
| SCHEMBL27277079 | 0.80 | CTRC (0.56) | PPARGPPARACTRC | |
| SCHEMBL10419468 | 0.80 | PPARG (0.67) | PPARGPPARACTRC | |
| SCHEMBL9614323 | 0.79 | PPARG (0.58) | PPARGPPARA | |
| SCHEMBL11576734 | 0.78 | CTRC (0.58) | PPARGPPARACTRC | |
| SCHEMBL9613976 | 0.78 | MMP2 (0.51) | PPARGPPARAMTNR1AMTNR1B | |
| SCHEMBL28352624 | 0.78 | PPARG (0.54) | PPARGPPARAFOLH1CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145611-A | Diabetes | BOEHRINGER MANNHEIM GMBH (DE) | 1992-09-08 | — | — | US | disclosed |