Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.48 |
| ▸ | PPARA | Q07869 | 13/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9614136 | 0.85 | PPARG (0.56) | PPARGPPARAFOLH1MTNR1AMTNR1B | |
| SCHEMBL9613840 | 0.85 | PPARG (0.59) | PPARGPPARATDP1FOLH1CTRC | |
| SCHEMBL9614239 | 0.81 | PPARG (0.63) | PPARGPPARACTRC | |
| SCHEMBL9696796 | 0.81 | PPARG (0.63) | PPARGPPARACTRC | |
| SCHEMBL9614339 | 0.80 | PPARA (0.68) | PPARGPPARA | |
| SCHEMBL28631721 | 0.79 | PPARG (0.60) | PPARGPPARAMAPTTDP1L3MBTL1 | |
| SCHEMBL9696319 | 0.78 | PPARG (0.61) | PPARGPPARACTRCSMN1; SMN2 | |
| SCHEMBL8935640 | 0.76 | SMN1; SMN2 (0.59) | PPARGPPARAMAPTTDP1L3MBTL1 | |
| SCHEMBL8935642 | 0.76 | SMN1; SMN2 (0.59) | PPARGPPARAMAPTTDP1L3MBTL1 | |
| SCHEMBL9696349 | 0.76 | PPARG (0.45) | PPARGPPARASLC6A9CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017435-A1 | OPTICALLY ACTIVE CARBOXYLIC ACIDS AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1992-10-15 | — | — | WO | disclosed |
| EP-0507238-A1 | Optically active carboxylic acids and medicinal preparations containing them | Roche Diagnostics GmbH (DE) | 1992-10-07 | — | — | EP | disclosed |