Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.42 |
| ▸ | RXRB | P28702 | 2/20 | 0.42 |
| ▸ | RXRG | P48443 | 2/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10533225 | 0.78 | NR1H4 (0.67) | NR1H4EPHX2SLC13A5RXRARXRB | |
| SCHEMBL10472979 | 0.76 | NR1H4 (0.65) | NR1H4EPHX2SLC13A5RXRARXRB | |
| SCHEMBL1453852 | 0.76 | NR1H4 (0.73) | NR1H4EPHX2SLC13A5RXRARXRB | |
| SCHEMBL9614255 | 0.76 | STS (0.42) | NR1H4SLC13A5GRIA4HDAC3HDAC1 | |
| SCHEMBL1471504 | 0.75 | NR1H4 (0.51) | NR1H4EPHX2SLC13A5RXRARXRB | |
| SCHEMBL9857963 | 0.74 | ALDH1A1 (0.44) | NR1H4SLC13A5HDAC1ESRRG | |
| SCHEMBL846131 | 0.73 | NR1H4 (0.71) | NR1H4EPHX2SLC13A5RXRARXRB | |
| SCHEMBL2484298 | 0.72 | MMP12 (0.49) | NR1H4EPHX2SLC13A5RXRARXRB | |
| SCHEMBL2484440 | 0.72 | MMP12 (0.49) | NR1H4EPHX2SLC13A5RXRARXRB | |
| SCHEMBL11143911 | 0.69 | SRD5A2 (0.53) | NR1H4EPHX2RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145611-A | Diabetes | BOEHRINGER MANNHEIM GMBH (DE) | 1992-09-08 | — | — | US | disclosed |