Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 2/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.42 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857963 | 0.88 | ALDH1A1 (0.44) | SLC13A5PPARGPPARAESRRGALDH1A1 | |
| SCHEMBL27274785 | 0.86 | PPARA (0.47) | S1PR2S1PR1S1PR3PPARGPPARA | |
| SCHEMBL27273547 | 0.86 | S1PR2 (0.46) | S1PR2S1PR1S1PR3ALDH1A1S1PR4 | |
| SCHEMBL9613995 | 0.78 | PPARA (0.53) | S1PR2S1PR1S1PR3PPARGPPARA | |
| SCHEMBL9614252 | 0.76 | NR1H4 (0.48) | SLC13A5GRIA4ESRRGHDAC3HDAC1 | |
| SCHEMBL9614269 | 0.76 | PPARA (0.51) | S1PR2S1PR1S1PR3PPARGPPARA | |
| SCHEMBL10420392 | 0.75 | TRPA1 (0.48) | S1PR2S1PR1S1PR3HDAC3HDAC1 | |
| SCHEMBL9613974 | 0.75 | TRPA1 (0.48) | S1PR2S1PR1S1PR3HDAC3HDAC1 | |
| SCHEMBL9614023 | 0.75 | PPARA (0.47) | S1PR2S1PR1S1PR3PPARGPPARA | |
| SCHEMBL9614242 | 0.74 | TDP1 (0.43) | S1PR2S1PR1S1PR3ALDH1A1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145611-A | Diabetes | BOEHRINGER MANNHEIM GMBH (DE) | 1992-09-08 | — | — | US | disclosed |