Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRAT | P43155 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9615750 | 0.94 | CA1 (0.42) | CRATCA1NFKB1KDM4EMAPT | |
| Butane SCHEMBL22204302 | 0.85 | NFKB1 (0.43) | CRATCA1NFKB1KDM4EMAPT | |
| SCHEMBL6967366 | 0.73 | KDM4E (0.39) | CRATNFKB1KDM4EMAPTTHRB | |
| SCHEMBL143910 | 0.71 | KDM4E (0.48) | NFKB1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL29078947 | 0.70 | ALDH1A1 (0.37) | CRATCA1NFKB1KDM4EMAPT | |
| SCHEMBL29078948 | 0.70 | ALDH1A1 (0.37) | CRATCA1NFKB1KDM4EMAPT | |
| SCHEMBL11433897 | 0.70 | CA1 (0.40) | CRATCA1NFKB1KDM4EMAPT | |
| SCHEMBL9614381 | 0.69 | KDM4E (0.46) | NFKB1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL1471075 | 0.67 | SMN1; SMN2 (0.42) | CRATCA1NFKB1KDM4EMAPT | |
| SCHEMBL3869217 | 0.67 | KDM4E (0.44) | NFKB1KDM4EMAPTTHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462980-A4 | PLATINUM PHARMACEUTICAL AGENTS | — | 1992-03-11 | — | — | EP | disclosed |
| EP-0462980-A1 | PLATINUM PHARMACEUTICAL AGENTS | GEORGETOWN UNIVERSITY (US) | 1992-01-02 | — | — | EP | disclosed |
| US-4946954-A | ANTICARCINOGENIC AGENTS | GEORGETOWN UNIVERSITY (US) | 1990-08-07 | — | — | US | disclosed |
| WO-1990008157-A1 | PLATINUM PHARMACEUTICAL AGENTS | GEORGETOWN UNIVERSITY (US) | 1990-07-26 | — | — | WO | disclosed |