Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28965644 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MAPTGAAKDM4ESMN1; SMN2 | |
| SCHEMBL3472630 | 0.74 | ALDH1A1 (0.60) | ALDH1A1MAPTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL5424142 | 0.71 | LMNA (0.71) | ALDH1A1MAPTATMGAASMN1; SMN2 | |
| SCHEMBL28965728 | 0.70 | ALDH1A1 (0.60) | ALDH1A1MAPTPOLBSMN1; SMN2LMNA | |
| SCHEMBL3756850 | 0.69 | CCNB2 (0.41) | ALDH1A1MAPTGAAKDM4ESMN1; SMN2 | |
| SCHEMBL861881 | 0.69 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNAADORA2BMAPK1 | |
| SCHEMBL21177057 | 0.69 | TSHR (0.59) | ALDH1A1MAPTATMGAAKDM4E | |
| SCHEMBL17882590 | 0.68 | TSHR (0.48) | ALDH1A1MAPTGAAKDM4EPOLB | |
| SCHEMBL16792773 | 0.68 | ALDH1A1 (0.45) | ALDH1A1MAPTATMSMN1; SMN2LMNA | |
| SCHEMBL5431370 | 0.68 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4ESMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520024-A1 | QUINOXALINE COMPOUNDS AND THEIR PREPARATION AND USE. | NOVO NORDISK AS (DK) | 1992-12-30 | — | — | EP | disclosed |
| WO-1991013878-A1 | QUINOXALINE COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1991-09-19 | — | — | WO | disclosed |