Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | TP53 | P04637 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CBX7 | O95931 | 1/20 | 0.44 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.44 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5424142 | 0.73 | LMNA (0.71) | ALDH1A1LMNAKMT2ASMN1; SMN2HTT | |
| SCHEMBL12061417 | 0.73 | NPC1 (0.64) | ALDH1A1TP53LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL28965644 | 0.72 | ALDH1A1 (0.54) | ALDH1A1TP53LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL25307601 | 0.72 | L3MBTL1 (0.58) | ALDH1A1TP53KMT2AHTTCBX7 | |
| SCHEMBL4423632 | 0.72 | TSPO (0.57) | ALDH1A1TP53LMNAKMT2APOLB | |
| SCHEMBL4420217 | 0.71 | TP53 (0.58) | ALDH1A1TP53LMNAKMT2APOLB | |
| SCHEMBL750636 | 0.71 | ALDH1A1 (0.53) | ALDH1A1TP53LMNAKMT2APOLB | |
| SCHEMBL9614538 | 0.70 | ALDH1A1 (0.49) | ALDH1A1LMNAKMT2APOLBSMN1; SMN2 | |
| SCHEMBL25865290 | 0.70 | KMO (0.52) | ALDH1A1TP53MAPTCBX7CDYL | |
| SCHEMBL5208539 | 0.70 | ASAH1 (0.52) | ALDH1A1TP53LMNAKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605476-A | Substituted tricyclic compounds | 鲁宾有限公司（IN） | 2023-01-13 | — | — | CN | disclosed |