Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 2/20 | 0.45 |
| ▸ | EIF4EBP1 | Q13541 | 6/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL958494 | 0.87 | MAPT (0.46) | MRGPRX4LMNAMAPTEIF4EBP1NPC1 | |
| SCHEMBL959140 | 0.85 | MRGPRX4 (0.48) | MRGPRX4LMNAMAPT | |
| SCHEMBL960007 | 0.83 | LMNA (0.39) | MRGPRX4LMNAMAPTEIF4EBP1 | |
| SCHEMBL959490 | 0.80 | MRGPRX4 (0.53) | MRGPRX4LMNAMAPTTTREIF4EBP1 | |
| SCHEMBL959319 | 0.80 | MRGPRX4 (0.61) | MRGPRX4MAPTTTRPTGER1CYP2C9 | |
| SCHEMBL958823 | 0.74 | MRGPRX4 (0.49) | MRGPRX4LMNAMAPTTTRPTGER1 | |
| SCHEMBL959742 | 0.73 | HPGD (0.50) | LMNAMAPTTTRL3MBTL1 | |
| SCHEMBL959343 | 0.72 | MRGPRX4 (0.53) | MRGPRX4MAPTTTRPTGER1L3MBTL1 | |
| SCHEMBL957915 | 0.70 | MRGPRX4 (0.50) | MRGPRX4MAPTTTRPTGER1CYP2C9 | |
| SCHEMBL31568461 | 0.70 | MRGPRX4 (1.00) | MRGPRX4LMNAMAPTTTRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009421-A1 | COMPOUND HAVING 6-MEMBERED AROMATIC RING | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-01-13 | — | — | US | disclosed |
| EP-2253618-A1 | COMPOUND HAVING 6-MEMBERED AROMATIC RING | Takeda Pharmaceutical Company Limited (JP) | 2010-11-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009421-A1 | COMPOUND HAVING 6-MEMBERED AROMATIC RING | GPR4, NR3C2, NR5A2 | MRGPRX4 133/4885LMNA 4498/4885MAPT 4154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.