SCHEMBL961469

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25567580	0.87	ADORA2A (0.46)	LMNAMAPTALDH1A1ROCK2ADORA2A
	SCHEMBL14104064	0.85	CYP1A2 (0.51)	LMNAMAPTALDH1A1ADORA2ACYP3A4
	SCHEMBL29395996	0.85	CYP1A2 (0.51)	LMNAMAPTALDH1A1ADORA2ACYP3A4
	SCHEMBL12112029	0.82	ADORA2A (0.40)	LMNAMAPTALDH1A1ROCK2ADORA2A
	SCHEMBL873954	0.81	LMNA (0.59)	LMNAMAPTALDH1A1ROCK2ADORA2A
	SCHEMBL30460177	0.79	PIK3CA (0.70)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL22287875	0.79	PIK3CA (0.70)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL14103869	0.78	RAB9A (0.47)	MAPTALDH1A1PIK3CAMTORMEN1
	SCHEMBL960250	0.78	PIK3CA (0.59)	LMNAADORA2ACYP3A4PIK3CAMTOR
	SCHEMBL259607	0.76	RAB9A (0.55)	LMNAMAPTALDH1A1ADORA2AGAPDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.