Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.35 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17291026 | 0.87 | PSIP1 (0.39) | PSIP1COMTAPEX1LMNAHTT | |
| SCHEMBL692167 | 0.83 | TTR (0.38) | COMTMYCSMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL1900933 | 0.78 | COMT (0.39) | PSIP1COMTAPEX1CYP1A2CYP3A4 | |
| SCHEMBL5152547 | 0.78 | GABRA1 (0.39) | SMN1; SMN2MAPT | |
| SCHEMBL14676186 | 0.77 | PSIP1 (0.35) | PSIP1 | |
| SCHEMBL5150091 | 0.76 | MYC (0.36) | MYCLMNASMN1; SMN2CYP1A2HPGD | |
| SCHEMBL11798388 | 0.76 | KDM4E (0.40) | MYCMEN1LMNAHTTKMT2A | |
| SCHEMBL8510866 | 0.75 | TDP1 (0.32) | LMNAHTTSMN1; SMN2MAPTTTR | |
| SCHEMBL1900932 | 0.74 | PSIP1 (0.38) | PSIP1COMTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5357823 | 0.74 | DAO (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471702-A1 | WATER-SOLUBLE REACTIVE DYES FOR FIBRES, THEIR PREPARATION AND USE. | HOECHST AG (DE) | 1992-02-26 | — | — | EP | disclosed |