SCHEMBL692167

SCHEMBL692167

O=S(=O)(O)c1[c]cccc1S(=O)(=O)O

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.38
MYC P01106 1/20 0.36
TSHR P16473 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
CYP2D6 P10635 1/20 0.32
FABP4 P15090 1/20 0.32
CCNA2 P20248 1/20 0.32
CDK2 P24941 1/20 0.32
MAPK14 Q16539 1/20 0.32
NR4A1 P22736 1/20 0.31
CYP1A2 P05177 1/20 0.30
COMT P21964 1/20 0.30
PGAM1 P18669 1/20 0.30
AURKA O14965 1/20 0.30
AURKB Q96GD4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9614697 0.83 PSIP1 (0.35) TTRMYCSMN1; SMN2CYP2D6CYP1A2
SCHEMBL8510866 0.83 TDP1 (0.32) TTRTSHRSMN1; SMN2
SCHEMBL8510865 0.83 CYP2D6 (0.34) TTRMYCTSHRSMN1; SMN2CYP2D6
SCHEMBL11692937 0.81 TSHR (0.45) MYCTSHRSMN1; SMN2
SCHEMBL11798388 0.80 KDM4E (0.40) MYC
SCHEMBL11798381 0.79 HSD11B1 (0.39) MYC
SCHEMBL691617 0.78 ALDH1A1 (0.35) TSHRSMN1; SMN2
SCHEMBL176809 0.78 TTR (0.38) TTRMYCTSHRSMN1; SMN2FABP4
SCHEMBL483018 0.78 SMN1; SMN2 (0.34) TSHRSMN1; SMN2CDK2COMTAURKA
SCHEMBL458582 0.77 TTR (0.46) TTRMYCTSHRSMN1; SMN2FABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 330 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102405036-B Keratin dyeing compositions comprising free radical scavengers and uses thereof PROCTER & GAMBLE 2013-09-18 CN claimed
CN-101076569-B Phthalocyanines and their use in ink-jet printers FUJIFILM IMAGING COLORANTS LTD. (GB) 2011-12-14 CN claimed
CN-100569864-C Mixtures of fiber-reactive azo dyes, process for their preparation and their use DYSTAR TEXTILFARBEN GMBH & CO (DE) 2009-12-16 CN claimed
US-7381256-B2 Mixtures of fiber-reactive azo dyes, their production and their use DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2008-06-03 US claimed
CN-101076570-A Phthalocyanines and their use in ink-jet printing FUJIFILM IMAGING COLORANTS LTD (GB) 2007-11-21 CN claimed
CN-101076569-A Phthalocyanines and their use in ink-jet printers FUJIFILM IMAGING COLORANTS LTD (GB) 2007-11-21 CN claimed
US-20070209540-A1 Mixtures Of Fiber-Reactive Azo Dyes, Their Production And Their Use DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2007-09-13 US claimed
CN-1918246-A Mixtures of fiber-reactive azo dyes, their production and their use DYSTAR TEXTILFARBEN GMBH & CO (DE) 2007-02-21 CN claimed
EP-1737915-A1 MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PRODUCTION AND THEIR USE DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2007-01-03 EP claimed
WO-2005100485-A1 MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PRODUCTION AND THEIR USE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2005-10-27 WO claimed
EP-0073406-B1 WATER-SOLUBLE MONOAZO PYRAZOLONE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1985-03-20 EP claimed
EP-0120399-A2 Process for the preparation of acid dyes of the triphenylmethane series poor in electrolyte CASSELLA Aktiengesellschaft (DE) 1984-10-03 EP claimed
EP-0102325-A1 Monoazo dyestuffs, their preparation and their use CIBA-GEIGY AG (CH) 1984-03-07 EP claimed
EP-0101408-A1 Monoazo dyestuffs, their preparation and their use CIBA-GEIGY AG (CH) 1984-02-22 EP claimed
US-4250090-A COLORFASTNESS; WETFASTNESS; ACID AZO DYES BASF AKTIENGESELLSCHAFT (DE) 1981-02-10 US claimed
US-4069218-A COTTON CIBA-GEIGY CORPORATION (US) 1978-01-17 US claimed
US-4028112-A MEROCYANINE DYE WITH OXAZOLE NUCLEUS FUJI PHOTO FILM CO., LTD. (JA) 1977-06-07 US claimed
US-3966705-A Disulfo naphthalene containing fiber-reactive tetrazo dyes CIBA-GEIGY CORPORATION (US) 1976-06-29 US claimed
US-3957751-A WATER-SOLUBLE REACTIVE DYESTUFFS OF THE MONOAZO SERIES CONTAINING AN ACTIVE METHYLENE COUPLING COMPONENT HOECHST AKTIENGESELLSCHAFT (DT) 1976-05-18 US claimed
US-3951965-A OPTICAL BRIGHTENERS HOECHST AKTIENGESELLSCHAFT (DT) 1976-04-20 US claimed