Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1360134 | 0.89 | HPGD (0.47) | HPGDALDH1A1SMN1; SMN2RAB9ACYP1A2 | |
| SCHEMBL6013194 | 0.85 | HPGD (0.44) | HPGDALDH1A1SMN1; SMN2RAB9ACYP1A2 | |
| SCHEMBL9259815 | 0.84 | HPGD (0.43) | HPGDALDH1A1SMN1; SMN2RAB9ACYP1A2 | |
| SCHEMBL709348 | 0.82 | HPGD (0.45) | HPGDALDH1A1SMN1; SMN2RAB9ACYP1A2 | |
| SCHEMBL9564059 | 0.71 | HPGD (0.45) | HPGDALDH1A1SMN1; SMN2RAB9ACYP1A2 | |
| SCHEMBL1361288 | 0.70 | ALDH1A1 (0.37) | HPGDALDH1A1SMN1; SMN2MAPTPOLB | |
| SCHEMBL10874560 | 0.70 | LMNA (0.41) | HPGDALDH1A1SMN1; SMN2RAB9ACYP1A2 | |
| SCHEMBL9563934 | 0.70 | HPGD (0.41) | HPGDALDH1A1SMN1; SMN2RAB9ACYP1A2 | |
| SCHEMBL7045870 | 0.69 | HPGD (0.43) | HPGDALDH1A1SMN1; SMN2RAB9ACYP1A2 | |
| SCHEMBL9563923 | 0.69 | ALDH1A1 (0.43) | HPGDALDH1A1SMN1; SMN2RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0484328-A1 | PROCESS FOR THE PREPARATION OF 2,4,6-TRIIODO-5-AMINO-N-ALKYLISOPHTHALAMIC ACID AND 2,4,6-TRIIODO-5-AMINO-ISOPHTHALAMIDE COMPOUNDS. | MALLINCKRODT INC (US) | 1992-05-13 | — | — | EP | disclosed |