Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6657819 | 0.89 | ALDH1A1 (0.58) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| Isopropyl Alcohol SCHEMBL2167428 | 0.85 | ALDH1A1 (0.54) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL14529015 | 0.80 | ALDH1A1 (0.61) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL28527821 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL10298225 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| Isopropyl Alcohol SCHEMBL5560849 | 0.78 | ALDH1A1 (0.48) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL851166 | 0.78 | ALDH1A1 (0.66) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL1931817 | 0.77 | LMNA (0.58) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL7079626 | 0.77 | TDP1 (0.59) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL3595449 | 0.77 | LMNA (0.58) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0495011-A4 | HYDROPHILIC POLYURETHANE ELASTOMERS | — | 1992-08-12 | — | — | EP | claimed |
| EP-0495011-A1 | HYDROPHILIC POLYURETHANE ELASTOMERS | PolyMedica Industries, Inc. (US) | 1992-07-22 | — | — | EP | claimed |
| US-5118779-A | Drug delivery | POLYMEDICA INDUSTRIES, INC. (US) | 1992-06-02 | — | — | US | claimed |
| WO-1991005809-A1 | HYDROPHILIC POLYURETHANE ELASTOMERS | POLYMEDICA INDUSTRIES, INC. (US) | 1991-05-02 | — | — | WO | claimed |
| EP-0495011-A4 | HYDROPHILIC POLYURETHANE ELASTOMERS | — | 1992-08-12 | — | — | EP | disclosed |
| EP-0495011-A1 | HYDROPHILIC POLYURETHANE ELASTOMERS | PolyMedica Industries, Inc. (US) | 1992-07-22 | — | — | EP | disclosed |
| US-5118779-A | Drug delivery | POLYMEDICA INDUSTRIES, INC. (US) | 1992-06-02 | — | — | US | disclosed |
| WO-1991005809-A1 | HYDROPHILIC POLYURETHANE ELASTOMERS | POLYMEDICA INDUSTRIES, INC. (US) | 1991-05-02 | — | — | WO | disclosed |