O-Xylene

O-Xylene

SCHEMBL9614971

Cc1ccc(C)c(C)c1C.Cc1cccc(C)c1C.Cc1ccccc1C

nearest known ligand 0.62

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.62
ACHE P22303 2/20 0.62
TRPA1 O75762 2/20 0.50
ATM Q13315 1/20 0.50
CYP1A2 P05177 4/20 0.46
CYP2A6 P11509 3/20 0.46
ALDH1A1 P00352 3/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA7 P43166 2/20 0.43
CA9 Q16790 2/20 0.43
KEAP1 Q14145 1/20 0.43
NFE2L2 Q16236 1/20 0.43
RAPGEF4 Q8WZA2 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CYP3A4 P08684 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
MEN1 O00255 1/20 0.41
AKR1B10 O60218 1/20 0.41
ABCB11 O95342 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4071459 0.94 TRPA1 (0.55) TSHRACHETRPA1ATMCYP1A2
O-Xylene SCHEMBL3835918 0.94 TSHR (0.71) TSHRACHETRPA1ATMCYP1A2
SCHEMBL40704 0.87
SCHEMBL5494561 0.87 TRPA1 (0.61) TSHRACHETRPA1ATMCYP1A2
Ammonia Solution, Strong SCHEMBL9810941 0.83 TRPA1 (0.58) TSHRACHETRPA1ATMCYP1A2
Bromide SCHEMBL21173634 0.83 TRPA1 (0.58) TSHRACHETRPA1ATMCYP1A2
Benzene SCHEMBL22829865 0.83 TRPA1 (0.58) TSHRACHETRPA1ATMCYP1A2
Hydrochloric Acid SCHEMBL22194330 0.83 TRPA1 (0.58) TSHRACHETRPA1ATMCYP1A2
Ammonia Solution, Strong SCHEMBL2017512 0.83 TRPA1 (0.58) TSHRACHETRPA1ATMCYP1A2
SCHEMBL7695351 0.83 TRPA1 (0.58) TSHRACHETRPA1ATMCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4112839-A None JP disclosed
JP-H04112839-A PRODUCTION OF 2,6-DIMETHYLNAPHTHALENE TEIJIN LTD 1992-04-14 JP disclosed