Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9615034 | 0.97 | KMT2A (0.53) | KMT2AMEN1ALDH1A1AGTR1HTT | |
| SCHEMBL9615038 | 0.94 | KMT2A (0.57) | KMT2AMEN1ALDH1A1AGTR1HTT | |
| SCHEMBL9615033 | 0.88 | KMT2A (0.46) | KMT2AMEN1ALDH1A1AGTR1HTT | |
| SCHEMBL9371294 | 0.79 | MCL1 (0.46) | ALDH1A1LMNAMCL1 | |
| SCHEMBL9615051 | 0.78 | KMT2A (0.51) | KMT2AMEN1ALDH1A1AGTR1HTT | |
| SCHEMBL9154069 | 0.74 | KMT2A (0.48) | KMT2AMEN1ALDH1A1AGTR1HTT | |
| SCHEMBL9368883 | 0.73 | MCL1 (0.48) | MCL1 | |
| SCHEMBL9152137 | 0.73 | KMT2A (0.48) | KMT2AMEN1ALDH1A1AGTR1HTT | |
| SCHEMBL22694071 | 0.72 | ALDH1A1 (0.66) | KMT2AMEN1ALDH1A1AGTR1HTT | |
| Dinitrophenylene SCHEMBL27717249 | 0.71 | RAB9A (0.53) | KMT2AMEN1ALDH1A1AGTR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516849-A1 | INDOLE DERIVATIVES. | FUJISAWA PHARMACEUTICAL CO (JP) | 1992-12-09 | — | — | EP | disclosed |