Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9615034 | 0.91 | KMT2A (0.53) | KMT2AALDH1A1MEN1AGTR1HTT | |
| SCHEMBL9615028 | 0.88 | KMT2A (0.52) | KMT2AALDH1A1MEN1AGTR1HTT | |
| SCHEMBL9615038 | 0.85 | KMT2A (0.57) | KMT2AALDH1A1MEN1AGTR1HTT | |
| SCHEMBL9150381 | 0.75 | KMT2A (0.47) | KMT2AALDH1A1MEN1AGTR1HTT | |
| SCHEMBL9371294 | 0.73 | MCL1 (0.46) | ALDH1A1LMNA | |
| SCHEMBL9615051 | 0.72 | KMT2A (0.51) | KMT2AALDH1A1MEN1AGTR1HTT | |
| SCHEMBL9615042 | 0.72 | CNR1 (0.47) | ALDH1A1CYP1A2CYP2C19CNR1HPGD | |
| SCHEMBL1345750 | 0.71 | GPR17 (0.53) | KMT2AALDH1A1MEN1HTTHPGD | |
| SCHEMBL22694071 | 0.69 | ALDH1A1 (0.66) | KMT2AALDH1A1MEN1AGTR1HTT | |
| SCHEMBL9369708 | 0.69 | PPARG (0.44) | ALDH1A1CYP1A2CYP2C19CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516849-A1 | INDOLE DERIVATIVES. | FUJISAWA PHARMACEUTICAL CO (JP) | 1992-12-09 | — | — | EP | disclosed |