Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9149099 | 0.91 | KMT2A (0.49) | KMT2AMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9154069 | 0.88 | KMT2A (0.48) | KMT2AMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9152137 | 0.87 | KMT2A (0.48) | KMT2AMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9152716 | 0.85 | KMT2A (0.55) | KMT2AMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9150364 | 0.80 | RAB9A (0.49) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9615033 | 0.75 | KMT2A (0.46) | KMT2AMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9371289 | 0.73 | HTR6 (0.46) | KMT2AMEN1ALDH1A1L3MBTL1HTR1A | |
| SCHEMBL9149259 | 0.72 | TNFSF11 (0.50) | KMT2AMEN1ALDH1A1HTR1AHTR1D | |
| SCHEMBL9333981 | 0.72 | MEN1 (0.51) | KMT2AMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9156549 | 0.72 | AKR1C3 (0.46) | HTR1AHTR1DHTR1BHTR1FHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516849-B1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5283251-A | Testosterone 5a-reductase inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-02-01 | — | — | US | disclosed |
| WO-1991013060-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-05 | — | — | WO | disclosed |
| CN-1054250-A | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 1991-09-04 | — | — | CN | disclosed |