SCHEMBL9615439

SCHEMBL9615439

O=C1C=CC(=O)N1c1ccc(Cc2ccc(N3C(=O)C=CC3=O)c(Cc3ccc(N4C(=O)C=CC4=O)cc3)c2)cc1

nearest known ligand 0.68

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 18/20 0.68
FAAH O00519 7/20 0.68
G6PD P11413 1/20 0.44
TLR9 Q9NR96 1/20 0.44
HSP90AA1 P07900 1/20 0.42
PKM P14618 1/20 0.42
MAPK1 P28482 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
DDAH1 O94760 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2596734 0.87 MGLL (0.72) MGLLFAAHG6PDTLR9HSP90AA1
SCHEMBL19565018 0.83 MGLL (0.66) MGLLFAAHG6PDTLR9HSP90AA1
SCHEMBL114168 0.82 MGLL (1.00) MGLLFAAHHSP90AA1PKMMAPK1
SCHEMBL30104189 0.81 MGLL (0.59) MGLLFAAHG6PDTLR9HSP90AA1
SCHEMBL29929064 0.81 MGLL (0.59) MGLLFAAHG6PDTLR9HSP90AA1
SCHEMBL332215 0.81 MGLL (0.59) MGLLFAAHG6PDTLR9HSP90AA1
SCHEMBL19511516 0.77 MGLL (0.51) MGLLFAAHG6PDTLR9HSP90AA1
SCHEMBL21215695 0.77 MGLL (0.88) MGLLFAAHHSP90AA1PKMMAPK1
SCHEMBL30279692 0.77 MGLL (0.55) MGLLFAAHG6PDTLR9HSP90AA1
SCHEMBL1258019 0.77 MGLL (0.55) MGLLFAAHG6PDTLR9HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4142327-A None JP disclosed
JP-H04142327-A IMIDE RESIN COMPOSITION MITSUI PETROCHEM IND LTD 1992-05-15 JP disclosed