Naphthalene

Naphthalene

SCHEMBL9615518

c1ccc2ccccc2c1.c1cocn1.c1cocn1

nearest known ligand 0.40

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.40
ALOX12 P18054 1/20 0.40
CYP11B1 P15538 3/20 0.34
CYP11B2 P19099 3/20 0.34
CYP19A1 P11511 2/20 0.32
CYP17A1 P05093 1/20 0.32
PLAU P00749 2/20 0.32
NCF1 P14598 2/20 0.32
NOS2 P35228 2/20 0.32
BACE1 P56817 2/20 0.32
F12 P00748 1/20 0.32
NOS3 P29474 1/20 0.32
NOS1 P29475 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPK9 P45984 2/20 0.31
MAPK10 P53779 2/20 0.31
PLG P00747 1/20 0.31
MAPK8 P45983 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthalene SCHEMBL303948 1.00 CYP2A6 (0.40) CYP2A6ALOX12CYP11B1CYP11B2CYP19A1
Anthracene SCHEMBL26926677 0.91 ALDH1A1 (0.37) CYP2A6ALOX12CYP11B1CYP11B2CYP19A1
Oxazole SCHEMBL29213663 0.89
Isoquinoline SCHEMBL27772897 0.88 TNF (0.37) CYP11B1CYP11B2CYP19A1CYP17A1ALDH1A1
Phenanthrene SCHEMBL27708213 0.87 ALDH1A1 (0.50) CYP2A6PLAUNCF1NOS2BACE1
Triphenylene SCHEMBL21381928 0.85 LMNA (0.32) CYP2A6CYP11B1PLAUNCF1NOS2
Pyrene SCHEMBL3808718 0.84 ALDH1A1 (0.48) ALDH1A1
Oxazole SCHEMBL9215176 0.83 CYP2A6 (0.59) CYP2A6CYP11B1CYP11B2CYP19A1CYP17A1
Biphenyl SCHEMBL29228469 0.83 NOTUM (0.50) CYP2A6CYP19A1PLAUALDH1A1
Biphenyl SCHEMBL944174 0.83 NOTUM (0.50) CYP2A6CYP19A1PLAUALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5128238-A Developing both a negative silver halide color photographic material and an internal latent image type positive silver halide color photographic material with the same developer FUJI PHOTO FILM CO., LTD. (JP) 1992-07-07 US claimed
EP-0343604-A2 Method of forming color images Fuji Photo Film Co., Ltd. (JP) 1989-11-29 EP claimed
US-5128238-A Developing both a negative silver halide color photographic material and an internal latent image type positive silver halide color photographic material with the same developer FUJI PHOTO FILM CO., LTD. (JP) 1992-07-07 US disclosed
EP-0343604-A2 Method of forming color images Fuji Photo Film Co., Ltd. (JP) 1989-11-29 EP disclosed