Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 4/20 | 0.45 |
| ▸ | F9 | P00740 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9615760 | 0.82 | PPARG (0.51) | NPSR1KMT2APPARGHDAC8 | |
| SCHEMBL10390639 | 0.78 | MAPT (0.49) | MAPTKMT2APPARGMEN1 | |
| SCHEMBL9327978 | 0.76 | MAPT (0.52) | MAPTTP53MAPK1NPSR1KLK7 | |
| SCHEMBL9615672 | 0.76 | HSD17B10 (0.57) | MAPTPKMNPSR1KMT2APOLB | |
| SCHEMBL3521282 | 0.73 | FAAH (0.42) | MAPTPKMKMT2APPARGMEN1 | |
| SCHEMBL6663334 | 0.69 | ROCK2 (0.60) | PKMKMT2AHDAC8MEN1 | |
| SCHEMBL10176502 | 0.69 | ROCK2 (0.60) | PKMKMT2AHDAC8MEN1 | |
| SCHEMBL21880195 | 0.69 | ROCK2 (0.60) | PKMKMT2AHDAC8MEN1 | |
| SCHEMBL2610069 | 0.67 | KMT2A (0.54) | KLK7KMT2AMEN1 | |
| SCHEMBL10362109 | 0.67 | CYP19A1 (0.49) | MAPTMAPK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4154770-A | — | — | None | — | — | JP | disclosed |
| JP-H04154770-A | TRIAZOLECARBOXLIC ACID AMIDE DERIVATIVE AND AGRICULTURAL AND HORTICULTURAL GERMICIDE | HOKKO CHEM IND CO LTD | 1992-05-27 | — | — | JP | disclosed |