SCHEMBL9615760

SCHEMBL9615760

O=C(O)C(Cc1ccc(Cl)cc1)n1ccnn1

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPARG P37231 8/20 0.51
CYP19A1 P11511 2/20 0.49
PPARA Q07869 7/20 0.42
NPSR1 Q6W5P4 1/20 0.42
HSD17B10 Q99714 1/20 0.42
AADAT Q8N5Z0 1/20 0.39
KMT2A Q03164 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
SLC6A4 P31645 1/20 0.39
NOTUM Q6P988 1/20 0.38
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9615672 0.87 HSD17B10 (0.57) PPARGCYP19A1NPSR1HSD17B10AADAT
SCHEMBL10390639 0.84 MAPT (0.49) PPARGCYP19A1KMT2ASLC6A4NOTUM
SCHEMBL9615707 0.82 MAPT (0.51) PPARGNPSR1KMT2AHDAC8
SCHEMBL3521282 0.81 FAAH (0.42) PPARGCYP19A1PPARAKMT2ALMNA
SCHEMBL10362109 0.74 CYP19A1 (0.49) CYP19A1KMT2ANOTUMLMNA
SCHEMBL10842542 0.74 NPSR1 (0.75) PPARGPPARANPSR1HSD17B10AADAT
SCHEMBL3371114 0.72 CYP19A1 (0.50) CYP19A1KMT2ASLC6A4NOTUM
SCHEMBL4891449 0.72 FFAR1 (0.56) PPARGPPARA
SCHEMBL30887795 0.72 HDAC8 (0.44) PPARGHDAC8
SCHEMBL15532588 0.72 PPARG (0.40) PPARGCYP19A1HSD17B10KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4164084-A None JP disclosed
JP-H04164084-A TRIAZOLE DERIVATIVE AND AGRICULTURAL AND HORTICULTURAL GERMICIDE HOKKO CHEM IND CO LTD 1992-06-09 JP disclosed