Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 15/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.56 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4882025 | 0.94 | PPARG (0.53) | FFAR1FFAR4PPARGPPARAPPARD | |
| SCHEMBL9615672 | 0.81 | HSD17B10 (0.57) | PPARG | |
| SCHEMBL4739519 | 0.74 | FFAR1 (0.57) | FFAR1FFAR4PPARGPPARAPPARD | |
| SCHEMBL1745467 | 0.73 | FFAR1 (1.00) | FFAR1FFAR4 | |
| SCHEMBL6239573 | 0.72 | FFAR1 (0.76) | FFAR1FFAR4 | |
| SCHEMBL9615760 | 0.72 | PPARG (0.51) | PPARGPPARA | |
| SCHEMBL9491438 | 0.71 | FFAR1 (0.68) | FFAR1FFAR4MAOB | |
| SCHEMBL5375802 | 0.71 | PPARA (0.73) | FFAR1FFAR4PPARGPPARAPPARD | |
| SCHEMBL1745006 | 0.71 | FFAR1 (0.73) | FFAR1FFAR4PPARGPPARD | |
| SCHEMBL1746424 | 0.71 | FFAR1 (0.62) | FFAR1FFAR4PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893582-A2 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR USE IN TREATING METABOLIC DISORDERS | Amgen, Inc (US) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006127503-A2 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR USE IN TREATING METABOLIC DISORDERS | AMGEN INC (US) | 2006-11-30 | — | — | WO | disclosed |