Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycinebetaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycinebetaine SCHEMBL8772044 | 0.77 | TSHR (0.55) | TSHRALDH1A1LMNAAPEX1 | |
| SCHEMBL10777139 | 0.77 | — | — | |
| Glycinebetaine SCHEMBL11579913 | 0.75 | TSHR (0.52) | TSHRALDH1A1LMNAAPEX1 | |
| Glycinebetaine SCHEMBL11008697 | 0.73 | CPT2 (0.33) | TSHRALDH1A1LMNAAPEX1 | |
| Glycinebetaine SCHEMBL2520108 | 0.73 | LMNA (0.46) | TSHRALDH1A1LMNAAPEX1 | |
| Glycinebetaine SCHEMBL10425194 | 0.71 | TSHR (0.48) | TSHRALDH1A1LMNAAPEX1 | |
| Glycinebetaine SCHEMBL1617824 | 0.69 | TSHR (0.42) | TSHRALDH1A1LMNAAPEX1 | |
| Glycinebetaine SCHEMBL23794909 | 0.68 | TSHR (0.35) | TSHRALDH1A1LMNAAPEX1 | |
| Glycinebetaine SCHEMBL21647161 | 0.68 | TSHR (0.42) | TSHRALDH1A1LMNAAPEX1 | |
| Glycinebetaine SCHEMBL22499790 | 0.68 | TSHR (0.42) | TSHRALDH1A1LMNAAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112720-A | Color diffusion transfer photographic film unit with dye trapping layer | FUJI PHOTO FILM CO., LTD. (JP) | 1992-05-12 | — | — | US | disclosed |