SCHEMBL9615853

SCHEMBL9615853

CC(C)CCCC[C@H]1O[C@H]1COC(=O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
TDP1 Q9NUW8 2/20 0.43
MAPK1 P28482 2/20 0.41
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
CTSK P43235 1/20 0.41
LMNA P02545 1/20 0.41
CHRNB2 P17787 1/20 0.40
CHRNA5 P30532 1/20 0.40
CHRNA7 P36544 1/20 0.40
CHRNA4 P43681 1/20 0.40
ADRB2 P07550 1/20 0.40
ADRB1 P08588 1/20 0.40
ADRB3 P13945 1/20 0.40
NPC1 O15118 1/20 0.40
TSHR P16473 1/20 0.39
HIF1A Q16665 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A3 Q01959 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8914254 0.85 CTSK (0.52) ALDH1A1TDP1MAPK1POLBGAA
SCHEMBL8912909 0.85 CTSK (0.52) ALDH1A1TDP1MAPK1POLBGAA
SCHEMBL8913447 0.85 CTSK (0.52) ALDH1A1TDP1MAPK1POLBGAA
SCHEMBL12959082 0.82 LMNA (0.54) ALDH1A1TDP1MAPK1POLBGAA
SCHEMBL10409114 0.79 ALDH1A1 (0.47) ALDH1A1TDP1MAPK1CTSKLMNA
SCHEMBL9701017 0.77 PTPN1 (0.38) ALDH1A1TSHR
SCHEMBL4331527 0.77 TDP1 (0.73) ALDH1A1TDP1MAPK1LMNAADRB2
SCHEMBL10572764 0.77 ALDH1A1 (0.52) ALDH1A1TDP1MAPK1POLBGAA
SCHEMBL10572757 0.77 ALDH1A1 (0.52) ALDH1A1TDP1MAPK1POLBGAA
SCHEMBL28719426 0.76 ALDH1A1 (0.52) ALDH1A1TDP1MAPK1POLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4169577-A None JP disclosed
JP-H04169577-A NEW BENZOYL ESTER AND DETERMINATION OF OPTICAL PURITY USING THE ESTER NITTO DENKO CORP 1992-06-17 JP disclosed