Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 11/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27099942 | 0.86 | HRH1 (0.48) | KEAP1NFE2L2CHRM3CHRM2CHRM1 | |
| SCHEMBL28568634 | 0.86 | KEAP1 (0.45) | KEAP1NFE2L2POLBCHRM3CHRM2 | |
| SCHEMBL1951187 | 0.78 | ALDH1A1 (0.37) | KEAP1NFE2L2CHRM3ALDH1A1 | |
| SCHEMBL24409157 | 0.77 | CHRM3 (0.45) | KEAP1NFE2L2POLBCHRM3CHRM2 | |
| SCHEMBL14825632 | 0.75 | MTNR1A (0.35) | KEAP1NFE2L2CHRM3CHRM2CHRM1 | |
| SCHEMBL25454421 | 0.75 | CHRM3 (0.49) | KEAP1NFE2L2POLBCHRM3CHRM2 | |
| SCHEMBL14825603 | 0.73 | MTNR1A (0.35) | KEAP1NFE2L2CHRM3CHRM2CHRM1 | |
| SCHEMBL3180129 | 0.73 | CYP2C19 (0.46) | ALDH1A1 | |
| SCHEMBL435821 | 0.73 | ELANE (0.45) | ALDH1A1 | |
| SCHEMBL7636490 | 0.73 | ALDH1A1 (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4173812-A | — | — | None | — | — | JP | disclosed |
| JP-H04173812-A | NEW METHACRYLIC ACID DERIVATIVE AND ITS POLYMER | DAICEL CHEM IND LTD | 1992-06-22 | — | — | JP | disclosed |