Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14565012 | 0.84 | ALDH1A1 (0.75) | ALDH1A1HPGDSIGMAR1GLASMN1; SMN2 | |
| SCHEMBL8700563 | 0.84 | ALDH1A1 (1.00) | ALDH1A1HPGDSIGMAR1GLASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9683732 | 0.83 | ALDH1A1 (0.73) | ALDH1A1HPGDSIGMAR1GLASMN1; SMN2 | |
| SCHEMBL745069 | 0.78 | TNIK (0.57) | ALDH1A1HPGDGLASMN1; SMN2PKM | |
| SCHEMBL14565048 | 0.78 | ALDH1A1 (0.77) | ALDH1A1HPGDSIGMAR1GLASMN1; SMN2 | |
| SCHEMBL14565011 | 0.77 | ALDH1A1 (0.70) | ALDH1A1HPGDSIGMAR1GLASMN1; SMN2 | |
| SCHEMBL5171751 | 0.75 | ALDH1A1 (0.68) | ALDH1A1HPGDSMN1; SMN2PKMLMNA | |
| SCHEMBL474056 | 0.75 | ALDH1A1 (0.73) | ALDH1A1HPGDSIGMAR1SMN1; SMN2PKM | |
| SCHEMBL9470718 | 0.75 | ALDH1A1 (0.43) | ALDH1A1HPGDGLASMN1; SMN2TP53 | |
| SCHEMBL9485091 | 0.75 | SIGMAR1 (0.48) | ALDH1A1HPGDSIGMAR1GLASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4230272-A | — | — | None | — | — | JP | disclosed |
| US-20070054899-A1 | Aromatase inhibitor compounds and uses thereof | PARALLEL WIRELESS, INC. | 2007-03-08 | — | — | US | disclosed |
| US-20070054899-A1 | Aromatase inhibitor compounds and uses thereof | PARALLEL WIRELESS, INC. | 2007-03-08 | — | — | US | disclosed |
| US-5147883-A | Antiischemic, stroke | ADIR ET COMPAGNIE (FR) | 1992-09-15 | — | — | US | disclosed |
| JP-H04230272-A | NEW ACYLBENZOXAZOLINONE AND ITS PRODUCTION | ADIR | 1992-08-19 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070054899-A1 | Aromatase inhibitor compounds and uses thereof | CYP19A1, CYP17A1, HSD17B11 | ALDH1A1 207/4885HPGD 155/4885SIGMAR1 3852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.