Trolamine

Trolamine

SCHEMBL9616233

NC(N)=O.OCC(O)CO.OCCN(CCO)CCO

nearest known ligand 0.43

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Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.43
ALDH1A1 P00352 2/20 0.43
THRB P10828 1/20 0.36
KDM4E B2RXH2 2/20 0.35
MAPT P10636 1/20 0.35
ALOX15 P16050 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PNP P00491 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolamine SCHEMBL6524533 0.87 LMNA (0.56) LMNAALDH1A1THRBKDM4EMAPT
Trolamine SCHEMBL28100199 0.85 LMNA (0.53) LMNAALDH1A1THRBKDM4EMAPT
Trolamine SCHEMBL28274608 0.85 LMNA (0.53) LMNAALDH1A1THRBKDM4EMAPT
Trolamine SCHEMBL14990729 0.84 KDM4E (0.44) LMNAALDH1A1KDM4EMAPTALOX15
Glycerin SCHEMBL9064954 0.82 LMNA (0.56) LMNAALDH1A1THRBMAPT
Glycerin SCHEMBL8328163 0.82 LMNA (0.64) LMNAALDH1A1THRBMAPT
Glycerin SCHEMBL4538901 0.82 LMNA (0.64) LMNAALDH1A1THRBMAPT
Trolamine SCHEMBL28109599 0.80 LMNA (0.47) LMNAALDH1A1THRBKDM4E
Trolamine SCHEMBL11803329 0.79 MAPT (0.41) LMNAALDH1A1KDM4EMAPTALOX15
Glycerin SCHEMBL11032789 0.79 LMNA (0.60) LMNAALDH1A1THRBKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5118937-A Process and device for the laser desorption of an analyte molecular ions, especially of biomolecules FINNIGAN MAT GMBH (DE) 1992-06-02 US disclosed