Trolamine

Trolamine

SCHEMBL28274608

B.OCC(O)CO.OCCN(CCO)CCO

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.53
ALDH1A1 P00352 2/20 0.53
THRB P10828 1/20 0.43
KDM4E B2RXH2 3/20 0.35
MAPT P10636 3/20 0.32
TSHR P16473 1/20 0.32
ALOX15 P16050 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
PNP P00491 2/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolamine SCHEMBL6524533 0.97 LMNA (0.56) LMNAALDH1A1THRBKDM4EMAPT
Trolamine SCHEMBL28100199 0.94 LMNA (0.53) LMNAALDH1A1THRBKDM4EMAPT
Trolamine SCHEMBL28109599 0.89 LMNA (0.47) LMNAALDH1A1THRBKDM4ETSHR
Trolamine SCHEMBL27661615 0.87 TDP1 (0.50) LMNAALDH1A1THRBKDM4EMAPT
Trolamine SCHEMBL9616233 0.85 LMNA (0.43) LMNAALDH1A1THRBKDM4EMAPT
Trolamine SCHEMBL27439255 0.83 ALDH1A1 (0.41) LMNAALDH1A1THRBKDM4EMAPT
Glycerin SCHEMBL5691791 0.81 LMNA (0.39) LMNAALDH1A1THRBKDM4ETSHR
Trolamine SCHEMBL29008328 0.81 MAPT (0.39) THRBKDM4EMAPTTSHRALOX15
Trolamine SCHEMBL8416714 0.80 MAPT (0.44) ALDH1A1KDM4EMAPTTSHRALOX15
SCHEMBL3279037 0.80 KDM4E (0.47) LMNAALDH1A1THRBKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106188980-B A kind of clear flexible PVC film and preparation method thereof 江阴市富华包装材料有限公司 2019-02-01 CN claimed