Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5935686 | 0.81 | TP53 (0.53) | L3MBTL1TP53TNKS2HTTKMT2A | |
| SCHEMBL14636999 | 0.81 | KMT2A (0.41) | L3MBTL1TP53TNKS2HTTKMT2A | |
| SCHEMBL9487922 | 0.80 | PARP1 (0.51) | L3MBTL1TP53ALDH1A1KDM4E | |
| SCHEMBL15427229 | 0.79 | L3MBTL1 (0.51) | L3MBTL1TP53TNKS2HTTADORA3 | |
| SCHEMBL18294954 | 0.78 | SMN1; SMN2 (0.55) | L3MBTL1TP53TNKS2HTTKMT2A | |
| SCHEMBL4283741 | 0.75 | L3MBTL1 (0.41) | L3MBTL1TP53TNKS2HTTADORA3 | |
| SCHEMBL25778574 | 0.75 | KDM4E (0.55) | L3MBTL1TP53HTTKMT2ALMNA | |
| SCHEMBL12143535 | 0.74 | L3MBTL1 (0.46) | L3MBTL1TP53TNKS2HTTKMT2A | |
| SCHEMBL2020536 | 0.72 | — | — | |
| SCHEMBL172127 | 0.72 | ALDH1A1 (0.58) | L3MBTL1TNKS2KMT2ALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514192-A1 | Antihypertensive benzofuran derivatives, substituted by varied N-pyrimidinyl- or N-imidazolyl-methyl groups | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |