Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | PTGIR | P43119 | 2/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 7/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL964416 | 1.00 | MEN1 (0.46) | MEN1KMT2AGALR3PTGIRPTGER2 | |
| SCHEMBL961642 | 1.00 | MEN1 (0.46) | MEN1KMT2AGALR3PTGIRPTGER2 | |
| SCHEMBL14514295 | 0.87 | MEN1 (0.59) | MEN1KMT2AGALR3PTGIRPTGER2 | |
| SCHEMBL3747302 | 0.86 | PTGIR (0.55) | MEN1KMT2AGALR3PTGIRPTGER2 | |
| SCHEMBL962042 | 0.86 | PTGIR (0.55) | MEN1KMT2AGALR3PTGIRPTGER2 | |
| SCHEMBL961743 | 0.86 | PTGIR (0.55) | MEN1KMT2AGALR3PTGIRPTGER2 | |
| SCHEMBL964095 | 0.83 | MEN1 (0.39) | MEN1KMT2AGALR3PTGER2PTGER4 | |
| SCHEMBL964097 | 0.83 | MEN1 (0.39) | MEN1KMT2AGALR3PTGER2PTGER4 | |
| SCHEMBL964098 | 0.83 | MEN1 (0.39) | MEN1KMT2AGALR3PTGER2PTGER4 | |
| Limaprost SCHEMBL23352904 | 0.82 | PTGIR (0.59) | MEN1KMT2APTGIRPTGER2PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110015238-A1 | BLOOD FLOW PROMOTERS FOR CAUDA EQUINA TISSUES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2011-01-20 | — | — | US | claimed |
| US-20070129327-A1 | Blood flow promoters for cauda equina tissues | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-06-07 | — | — | US | claimed |
| EP-1707208-A1 | BLOOD FLOW PROMOTERS FOR CAUDA EQUINA TISSUES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-10-04 | — | — | EP | claimed |
| US-8501793-B2 | Blood flow promoters for cauda equina tissues | ONO PHARMACEUTICAL CO., LTD. (JP) | 2013-08-06 | — | — | US | disclosed |
| US-20130143934-A1 | AGENT FOR REGENERATION AND/OR PROTECTION OF NERVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2013-06-06 | — | — | US | disclosed |
| US-8404858-B2 | Agent for regeneration and/or protection of nerves | ONO PHARMACEUTICAL CO., LTD. (JP) | 2013-03-26 | — | — | US | disclosed |
| EP-2494990-A1 | Agent for regeneration and/or protection of nerves | ONO PHARMACEUTICAL CO., LTD. (JP) | 2012-09-05 | — | — | EP | disclosed |
| EP-2308510-A1 | Agent for regeneration and/or protection of nerves | Ono Pharmaceutical Co., Ltd. (JP) | 2011-04-13 | — | — | EP | disclosed |
| US-20110059920-A1 | AGENT FOR REGENERATION AND/OR PROTECTION OF NERVES | ONO PHARMACEUTICAL CO., LTD (JP) | 2011-03-10 | — | — | US | disclosed |
| US-20110015238-A1 | BLOOD FLOW PROMOTERS FOR CAUDA EQUINA TISSUES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2011-01-20 | — | — | US | disclosed |
| US-7863263-B2 | Agent for regeneration and/or protection of nerves | ONO PHARMACEUTICAL CO., LTD. (JP) | 2011-01-04 | — | — | US | disclosed |
| US-7833995-B2 | Blood flow promoters for cauda equina tissues | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-11-16 | — | — | US | disclosed |
| US-20090227644-A1 | AGENT FOR REGENERATION AND/OR PROTECTION OF NERVES | ONO PHARMACEUTICAL CO., LTD (JP) | 2009-09-10 | — | — | US | disclosed |
| EP-1886693-A1 | AGENT FOR REGENERATION AND/OR PROTECTION OF NERVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-13 | — | — | EP | disclosed |
| US-20070129327-A1 | Blood flow promoters for cauda equina tissues | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-06-07 | — | — | US | disclosed |
| EP-1707208-A1 | BLOOD FLOW PROMOTERS FOR CAUDA EQUINA TISSUES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129327-A1 | Blood flow promoters for cauda equina tissues | PTGFR, PTGIS, PTGIR | MEN1 4761/4885KMT2A 1776/4885GALR3 1295/4885 |
| US-20130143934-A1 | AGENT FOR REGENERATION AND/OR PROTECTION OF NERVES | PTGER3, PTGER2, PTGER1 | MEN1 1724/4885KMT2A 4059/4885GALR3 448/4885 |
| US-20110015238-A1 | BLOOD FLOW PROMOTERS FOR CAUDA EQUINA TISSUES | PTGFR, PTGIS, PTGIR | MEN1 4761/4885KMT2A 1776/4885GALR3 1295/4885 |
| US-20090227644-A1 | AGENT FOR REGENERATION AND/OR PROTECTION OF NERVES | PTGER3, PTGER2, PTGER1 | MEN1 1724/4885KMT2A 4059/4885GALR3 448/4885 |
| US-20110059920-A1 | AGENT FOR REGENERATION AND/OR PROTECTION OF NERVES | PTGER3, PTGER2, PTGER1 | MEN1 1724/4885KMT2A 4059/4885GALR3 448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.