SCHEMBL964098

SCHEMBL964098

CCCC[C@H](C)C[C@@H](C=C[C@H]1CCC(=O)[C@@H]1CCCCC=CC(=O)O)OC1CCCCO1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.39
▸ GALR3 O60755 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ PTGER4 P35408 7/20 0.31
▸ PTGER2 P43116 7/20 0.31
▸ PTGER3 P43115 6/20 0.31
▸ HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL964097 1.00 MEN1 (0.39) MEN1GALR3KMT2APTGER4PTGER2
SCHEMBL964095 1.00 MEN1 (0.39) MEN1GALR3KMT2APTGER4PTGER2
SCHEMBL961642 0.83 MEN1 (0.46) MEN1GALR3KMT2APTGER4PTGER2
SCHEMBL964416 0.83 MEN1 (0.46) MEN1GALR3KMT2APTGER4PTGER2
SCHEMBL961640 0.83 MEN1 (0.46) MEN1GALR3KMT2APTGER4PTGER2
SCHEMBL10703299 0.78 PTGIR (0.34) PTGER4PTGER2PTGER3
SCHEMBL10952197 0.76 PTGDR2 (0.36) PTGER4PTGER2PTGER3
SCHEMBL11509792 0.75 MEN1 (0.42) MEN1GALR3KMT2APTGER4PTGER2
SCHEMBL11509790 0.75 MEN1 (0.42) MEN1GALR3KMT2APTGER4PTGER2
SCHEMBL14514295 0.75 MEN1 (0.59) MEN1GALR3KMT2APTGER4PTGER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8501793-B2 Blood flow promoters for cauda equina tissues ONO PHARMACEUTICAL CO., LTD. (JP) 2013-08-06 — — US disclosed
US-20110015238-A1 BLOOD FLOW PROMOTERS FOR CAUDA EQUINA TISSUES ONO PHARMACEUTICAL CO., LTD. (JP) 2011-01-20 — — US disclosed
US-7833995-B2 Blood flow promoters for cauda equina tissues ONO PHARMACEUTICAL CO., LTD. (JP) 2010-11-16 — — US disclosed
US-20070129327-A1 Blood flow promoters for cauda equina tissues ONO PHARMACEUTICAL CO., LTD. (JP) 2007-06-07 — — US disclosed
EP-1707208-A1 BLOOD FLOW PROMOTERS FOR CAUDA EQUINA TISSUES ONO PHARMACEUTICAL CO., LTD. (JP) 2006-10-04 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070129327-A1 Blood flow promoters for cauda equina tissues PTGFR, PTGIS, PTGIR MEN1 4761/4885GALR3 1295/4885KMT2A 1776/4885
US-20110015238-A1 BLOOD FLOW PROMOTERS FOR CAUDA EQUINA TISSUES PTGFR, PTGIS, PTGIR MEN1 4761/4885GALR3 1295/4885KMT2A 1776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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