Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GALR3 | O60755 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10977557 | 0.81 | HTR1D (0.44) | HTTPOLBTSHRHTR1DHTR1B | |
| SCHEMBL8763532 | 0.78 | ALDH1A1 (0.48) | POLBTSHRHTR1DHTR1BKMT2A | |
| SCHEMBL10979564 | 0.78 | ALDH1A1 (0.42) | HTTTSHRHTR1DHTR1BKMT2A | |
| SCHEMBL10817698 | 0.77 | HTT (0.44) | HTTPOLBTSHRHTR1DHTR1B | |
| SCHEMBL10815594 | 0.74 | FBP1 (0.34) | TSHRMAPTALDH1A1 | |
| SCHEMBL8763587 | 0.72 | ALDH1A1 (0.46) | POLBTSHRHTR1DHTR1BKMT2A | |
| SCHEMBL8762465 | 0.72 | ALDH1A1 (0.46) | POLBTSHRHTR1DHTR1BKMT2A | |
| SCHEMBL11505659 | 0.70 | HTT (0.55) | HTTPOLBTSHRKMT2AMAPT | |
| SCHEMBL7928401 | 0.70 | HTT (0.64) | HTTPOLBTSHRKMT2AMAPT | |
| SCHEMBL5158854 | 0.66 | HTT (1.00) | HTTPOLBTSHRKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0484325-A4 | AZIDO-SUBSTITUTED OCTOPAMINE AGONISTS AND THE USE THEREOF TO CONTROL INVERTEBRATE PESTS | — | 1992-06-24 | — | — | EP | disclosed |
| EP-0484325-A1 | AZIDO-SUBSTITUTED OCTOPAMINE AGONISTS AND THE USE THEREOF TO CONTROL INVERTEBRATE PESTS | THE GENERAL HOSPITAL CORPORATION (US) | 1992-05-13 | — | — | EP | disclosed |
| US-4892871-A | INSECTICIDE | THE GENERAL HOSPITAL CORPORATION (US) | 1990-01-09 | — | — | US | disclosed |
| WO-1989009542-A1 | AZIDO-SUBSTITUTED OCTOPAMINE AGONISTS AND THE USE THEREOF TO CONTROL INVERTEBRATE PESTS | THE GENERAL HOSPITAL CORPORATION (US) | 1989-10-19 | — | — | WO | disclosed |
| EP-0081923-B1 | 2-(TRISUBSTITUTED PHENYLIMINO)-IMIDAZOLINES | ALCON LABORATORIES, INC. (US) | 1987-01-21 | — | — | EP | disclosed |
| EP-0081924-B1 | TOPICAL COMPOSTIONS FOR LOWERING INTRAOCULAR PRESSURE | ALCON LABORATORIES, INC. (US) | 1986-02-19 | — | — | EP | disclosed |
| US-4517199-A | TREATMENT OF GLAUCOMA | ALCON LABORATORIES, INC. (US) | 1985-05-14 | — | — | US | disclosed |
| US-4515800-A | GLAUCOMA | ALCON MANUFACTURING, LTD. | 1985-05-07 | — | — | US | disclosed |
| US-4461904-A | 2-(Trisubstituted phenylimino)-imidazolines | ALCON LABORATORIES, INC. (US) | 1984-07-24 | — | — | US | disclosed |
| EP-0081924-A1 | Topical compostions for lowering intraocular pressure | ALCON LABORATORIES, INC. (US) | 1983-06-22 | — | — | EP | disclosed |
| EP-0081923-A2 | 2-(Trisubstituted phenylimino)-imidazolines | ALCON LABORATORIES, INC. (US) | 1983-06-22 | — | — | EP | disclosed |