Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 4/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | CBFB | Q13951 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.38 |
| ▸ | NCF1 | P14598 | 4/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399923 | 0.80 | ALDH1A1 (0.56) | ALDH1A1HSD17B10NCF1 | |
| SCHEMBL16537752 | 0.79 | MIF (0.43) | MIFAPPSLC22A12CBFBALDH1A1 | |
| SCHEMBL2335808 | 0.78 | GRM4 (0.44) | MIFAPPSLC22A12ALDH1A1CASP1 | |
| SCHEMBL21642369 | 0.76 | PDE2A (0.46) | MIFAPPALDH1A1CASP1CASP7 | |
| SCHEMBL8404871 | 0.76 | PTPN7 (0.51) | MIFALDH1A1HSD17B10PDE2ATSHR | |
| SCHEMBL621166 | 0.74 | SLC22A12 (0.47) | APPSLC22A12ALDH1A1CASP1CASP7 | |
| SCHEMBL5455329 | 0.73 | MIF (0.39) | MIFAPPSLC22A12CBFBALDH1A1 | |
| SCHEMBL16536568 | 0.73 | ALDH1A1 (0.45) | MIFAPPCBFBALDH1A1CASP1 | |
| SCHEMBL10330375 | 0.72 | ALDH1A1 (0.54) | ALDH1A1TSHRGRM4 | |
| SCHEMBL13030447 | 0.70 | NPC1 (0.51) | MIFAPPCBFBALDH1A1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0478545-A4 | 1,2,4-BENZOTRIAZINE OXIDES AS RADIOSENSITIZERS AND SELECTIVE CYTOTOXIC AGENTS | STANFORD RES INST INT (US) | 1992-08-05 | — | — | EP | disclosed |