Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 1/20 | 0.51 |
| ▸ | PDE2A | O00408 | 1/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.48 |
| ▸ | MIF | P14174 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9616706 | 0.76 | MIF (0.45) | PDE2AMIFTSHRHSD17B10ALDH1A1 | |
| SCHEMBL4076964 | 0.74 | PTPN7 (0.85) | PTPN7PDE2APDE3BPDE3AP2RY12 | |
| SCHEMBL8399923 | 0.74 | ALDH1A1 (0.56) | PTPN7HSD17B10MCL1LMNAMEN1 | |
| SCHEMBL7978731 | 0.71 | PTPN7 (0.66) | PTPN7PDE2APDE3BPDE3AP2RY12 | |
| SCHEMBL2907678 | 0.71 | PTPN7 (0.49) | PTPN7PDE2APDE3BPDE3AP2RY12 | |
| SCHEMBL9714119 | 0.70 | PTPN7 (0.71) | PTPN7MIFALOX15TSHRHSD17B10 | |
| SCHEMBL7293656 | 0.70 | TRIM24 (0.57) | PTPN7PDE2APDE3BPDE3AP2RY12 | |
| SCHEMBL339492 | 0.70 | ALOX15 (0.81) | PTPN7ALOX15TSHRHSD17B10MCL1 | |
| SCHEMBL2909583 | 0.70 | PTPN7 (0.48) | PTPN7PDE2APDE3BPDE3AP2RY12 | |
| SCHEMBL4019934 | 0.70 | PTPN7 (0.59) | PTPN7ALOX15TSHRHSD17B10MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856325-A | REDUCING INFLAMMATION BY INHIBITING PLA2 IN A MAMMAL | BOEHRINGER MANNHEIM GMBH (DE) | 1999-01-05 | — | — | US | disclosed |
| EP-0675881-B1 | Use of benzotriazines as PLA2-Inhibitors and new benzotriazines | BOEHRINGER MANNHEIM GMBH (DE) | 1997-03-19 | — | — | EP | disclosed |