Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11435942 | 0.84 | NPSR1 (0.41) | NPSR1KMT2AMEN1KDM1ASMN1; SMN2 | |
| SCHEMBL11440339 | 0.84 | TSHR (0.46) | NPSR1ADORA3KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14968052 | 0.76 | HTT (0.45) | NPSR1MAPTHTTPOLBKMT2A | |
| SCHEMBL7145020 | 0.74 | MAPT (0.41) | NPSR1MAPTHTTPOLBADORA3 | |
| SCHEMBL14968177 | 0.73 | CYP3A4 (0.51) | NPSR1MAPTHTTPOLBKMT2A | |
| SCHEMBL11448271 | 0.73 | TSHR (0.50) | ADORA3KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL14968287 | 0.72 | MAPT (0.41) | NPSR1MAPTHTTPOLBADORA3 | |
| SCHEMBL11438737 | 0.72 | ALDH1A1 (0.50) | NPSR1HTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL9616757 | 0.70 | ADORA3 (0.41) | NPSR1MAPTHTTPOLBADORA3 | |
| SCHEMBL4888244 | 0.68 | KDM1A (0.38) | NPSR1MAPTPOLBADORA3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235923-A | Esters of 3-substituted-2-(aminocarbonyl)oxiranecarboxylic acids as lipogenesis inhibitors | SHELL OIL COMPANY (US) | 1980-11-25 | — | — | US | disclosed |