Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7145021 | 0.84 | HTT (0.47) | HTTCYP3A4ALOX15MEN1KMT2A | |
| SCHEMBL873571 | 0.79 | HTT (0.45) | HTTCYP3A4ALOX15MEN1KMT2A | |
| SCHEMBL14968177 | 0.74 | CYP3A4 (0.51) | HTTCYP3A4ALOX15MEN1KMT2A | |
| SCHEMBL57715 | 0.74 | OPRM1 (0.49) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL4024963 | 0.71 | KLK7 (0.37) | CYP3A4OPRM1 | |
| SCHEMBL9358501 | 0.71 | HTT (0.39) | HTTCYP3A4ALOX15MEN1KMT2A | |
| SCHEMBL16110034 | 0.70 | CYP3A4 (0.44) | HTTCYP3A4ALOX15MEN1KMT2A | |
| SCHEMBL9511995 | 0.69 | ALDH1A1 (0.41) | HTTCYP3A4ALOX15MEN1KMT2A | |
| SCHEMBL14967770 | 0.69 | CYP3A4 (0.44) | HTTCYP3A4ALOX15MEN1KMT2A | |
| SCHEMBL14967798 | 0.68 | TSHR (0.47) | HTTMEN1KMT2AOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440723-A4 | PROCESS FOR PREPARING OPTICALLY ACTIVE GLYCIDATE ESTERS | — | 1992-05-20 | — | — | EP | disclosed |
| EP-0440723-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE GLYCIDATE ESTERS. | SEPRACOR INC (US) | 1991-08-14 | — | — | EP | disclosed |
| WO-1990004643-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE GLYCIDATE ESTERS | SEPRACOR, INC. (US) | 1990-05-03 | — | — | WO | disclosed |