Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | TOP2A | P11388 | 3/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749826 | 0.82 | KDM4E (0.52) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL10883769 | 0.81 | KDM4E (0.61) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL9749012 | 0.79 | KDM4E (0.61) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL9837564 | 0.77 | KDM4E (0.62) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL11037930 | 0.77 | KDM4E (0.67) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL9866403 | 0.76 | KDM4E (0.58) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL11185030 | 0.75 | KDM4E (0.71) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL11185357 | 0.75 | KDM4E (0.70) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL4370127 | 0.75 | LMNA (0.60) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL145406 | 0.74 | ALDH1A1 (0.52) | KDM4EHSD17B10ALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4208286-A | — | — | None | — | — | JP | disclosed |
| JP-H04208286-A | PYRROLO(1,2-I) (1,7)PHENANTHROLINE-2-CARBOXYLIC ACID COMPOUND AND ITS PRODUCTION | TOKYO TANABE CO LTD | 1992-07-29 | — | — | JP | disclosed |