Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.48 |
| ▸ | CA2 | P00918 | 5/20 | 0.48 |
| ▸ | TCF4 | P15884 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28612303 | 1.00 | CES2 (0.50) | CES2CES1CA1CA2TCF4 | |
| SCHEMBL8564034 | 0.80 | ALDH1A1 (0.57) | CES2CES1CA1CA2TCF4 | |
| SCHEMBL28606049 | 0.79 | ALDH1A1 (0.56) | CA1CA2MAPTMEN1RAB9A | |
| SCHEMBL4962948 | 0.78 | NQO2 (0.53) | CES2CES1CA1CA2TCF4 | |
| SCHEMBL9520221 | 0.78 | NQO2 (0.53) | CES2CES1CA1CA2TCF4 | |
| SCHEMBL3071944 | 0.78 | NQO2 (0.53) | CES2CES1CA1CA2TCF4 | |
| SCHEMBL6714893 | 0.78 | ALDH1A1 (0.45) | CES2CES1MAPTGSK3BMEN1 | |
| SCHEMBL28615101 | 0.78 | ALDH1A1 (0.45) | CES2CES1MAPTGSK3BMEN1 | |
| SCHEMBL28251903 | 0.78 | CES2 (0.50) | CES2CES1CA1CA2MAPT | |
| SCHEMBL28251902 | 0.78 | CES2 (0.50) | CES2CES1CA1CA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4026647-A | — | — | None | — | — | JP | disclosed |
| CN-113214283-B | Preparation method of furan macrocyclic compound, prepared furan macrocyclic compound and application | 华南理工大学 | 2022-09-30 | — | — | CN | disclosed |
| JP-H0426647-A | SUBSTITUTED ALPHA-BROMOCINNAMIC ALDEHYDES | T HASEGAWA CO LTD | 1992-01-29 | — | — | JP | disclosed |