SCHEMBL9617591

SCHEMBL9617591

Oc1cc(Cl)c(Oc2ccccc2)cc1Cl

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNLIP P16233 2/20 0.51
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
TTR P02766 3/20 0.47
MRGPRX4 Q96LA9 1/20 0.44
DPP4 P27487 1/20 0.43
ALDH1A1 P00352 1/20 0.43
ALOX12 P18054 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
GPR55 Q9Y2T6 1/20 0.43
HPGD P15428 2/20 0.43
TSHR P16473 1/20 0.43
HSD17B10 Q99714 1/20 0.43
NR1I2 O75469 1/20 0.43
LMNA P02545 1/20 0.43
PGR P06401 1/20 0.43
HSP90AA1 P07900 1/20 0.43
ADORA3 P0DMS8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10937945 0.88 CYP1A2 (0.53) PNLIPCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL10936260 0.86 TTR (0.53) PNLIPCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL10896708 0.85 MEN1 (0.48) PNLIPTTRHPGDTSHRHSD17B10
SCHEMBL3805626 0.80 TTR (0.65) PNLIPCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL8637175 0.78 PNLIP (0.43) PNLIPTTRALDH1A1HPGDNR1I2
SCHEMBL1027791 0.77 CAMK2A (0.54) PNLIPCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL10702237 0.77 LTA4H (0.52) PNLIPCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL10943177 0.77 CYP1A2 (0.58) PNLIPCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL10940178 0.77 CYP1A2 (0.62) CYP1A2CYP3A4CYP2C9CYP2C19TTR
SCHEMBL4514958 0.77 CYP1A2 (0.58) CYP1A2CYP3A4CYP2C9CYP2C19TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4253932-A None JP disclosed
JP-H04253932-A 2,5-DICHLORO-4-PHENOXYPHENOL DERIVATIVE, PRODUCTION THEREOF AND INJURIOUS ORGANISM CONTROL AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT SUMITOMO CHEM CO LTD 1992-09-09 JP disclosed