SCHEMBL8637175

SCHEMBL8637175

CC(C)Oc1ccc(Oc2cc(Cl)c(O)cc2Cl)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNLIP P16233 4/20 0.43
FFAR1 O14842 1/20 0.41
F2 P00734 1/20 0.41
F10 P00742 1/20 0.41
MPO P05164 1/20 0.40
TPO P07202 1/20 0.40
EPX P11678 1/20 0.40
LPO P22079 1/20 0.40
KMT2A Q03164 1/20 0.39
MAOB P27338 1/20 0.38
NR1I2 O75469 1/20 0.38
LMNA P02545 1/20 0.38
TTR P02766 1/20 0.38
PGR P06401 1/20 0.38
HSP90AA1 P07900 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
MAPT P10636 1/20 0.38
HSPA5 P11021 1/20 0.38
HPGD P15428 1/20 0.38
CBR1 P16152 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10896708 0.81 MEN1 (0.48) PNLIPF2F10MPOTPO
SCHEMBL21340747 0.80 HTR2A (0.47) FFAR1KMT2AMAPTHPGDALDH1A1
SCHEMBL9656840 0.80 FFAR1 (0.56) PNLIPFFAR1KMT2ANR1I2LMNA
SCHEMBL9617591 0.78 PNLIP (0.51) PNLIPF2F10NR1I2LMNA
SCHEMBL8634698 0.76 HTT (0.37) FFAR1F2F10MPOTPO
SCHEMBL3717795 0.75 ALDH1A1 (0.47) KMT2AMAOBLMNAHPGDPARP10
SCHEMBL8633666 0.75 MPO (0.36) FFAR1F2F10MPOTPO
SCHEMBL15242473 0.74 TTR (0.66) PNLIPFFAR1NR1I2LMNATTR
SCHEMBL15235668 0.71 PNLIP (0.40) PNLIPKMT2AMAOBLMNASLC6A2
SCHEMBL15242471 0.70 TTR (0.47) PNLIPFFAR1NR1I2LMNATTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed