Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | FABP2 | P12104 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705872 | 0.78 | FFAR1 (0.47) | CDK1CCNB1CCNA2CDK2PTGS1 | |
| SCHEMBL20773094 | 0.76 | CDK1 (0.44) | CDK1CCNB1CCNA2CDK2PTGS1 | |
| SCHEMBL7642234 | 0.76 | PTGS1 (0.46) | CDK1CCNB1CCNA2CDK2PTGS1 | |
| SCHEMBL7505997 | 0.75 | HDAC3 (0.46) | CDK1CCNB1CCNA2CDK2LMNA | |
| SCHEMBL7503214 | 0.75 | HDAC3 (0.42) | CDK1CCNB1CCNA2CDK2LMNA | |
| SCHEMBL28329663 | 0.73 | BCAT2 (0.47) | CDK1CCNB1CCNA2CDK2PTGS1 | |
| SCHEMBL13824200 | 0.73 | HTT (0.51) | CDK1CCNB1CCNA2CDK2PTGS1 | |
| SCHEMBL8574187 | 0.70 | MEN1 (0.51) | CDK1CCNB1CCNA2CDK2PTGS1 | |
| SCHEMBL29201438 | 0.67 | KAT6A (0.53) | PTGS1MEN1PTGS2KMT2AAKR1C3 | |
| SCHEMBL379725 | 0.67 | KMT2A (0.54) | MEN1KMT2ATSHRLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4253936-A | — | — | None | — | — | JP | disclosed |
| JP-4253936-A | — | — | None | — | — | JP | disclosed |
| JP-H04253936-A | 4-(2,4-DIFLUOROBIPHENYLYL)-2-METHYL-2-METHYL-4-OXOBUTANIC ACID DERIVATIVE 4-(2,4-DIFLUORBIPHENYLYL)-2-METHYL-4 OXUBUTANOICACID) AND ITS SALTS | VYZK USTAV PRO FARMACII A BIOCHEM STATNI POD | 1992-09-09 | — | — | JP | disclosed |
| JP-H04253936-A | 4-(2,4-DIFLUOROBIPHENYLYL)-2-METHYL-2-METHYL-4-OXOBUTANIC ACID DERIVATIVE 4-(2,4-DIFLUORBIPHENYLYL)-2-METHYL-4 OXUBUTANOICACID) AND ITS SALTS | VYZK USTAV PRO FARMACII A BIOCHEM STATNI POD | 1992-09-09 | — | — | JP | disclosed |