Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7505997 | 0.91 | HDAC3 (0.46) | FFAR1LMNACYP1A2HIF1ARAB9A | |
| SCHEMBL7503214 | 0.91 | HDAC3 (0.42) | FFAR1LMNACYP1A2HIF1ARAB9A | |
| SCHEMBL20773094 | 0.80 | CDK1 (0.44) | LMNACYP1A2HIF1ARAB9AGPR17 | |
| SCHEMBL9617615 | 0.78 | PTGES (0.39) | FFAR1LMNACYP1A2HIF1AGPR17 | |
| SCHEMBL28329663 | 0.77 | BCAT2 (0.47) | LMNACYP1A2HIF1ACDK1CCNB1 | |
| SCHEMBL7642234 | 0.77 | PTGS1 (0.46) | FFAR1LMNACYP1A2HIF1ASMN1; SMN2 | |
| SCHEMBL2088179 | 0.76 | CES2 (0.52) | FFAR1LMNACYP1A2HIF1ARAB9A | |
| SCHEMBL7441533 | 0.75 | CYP1A2 (0.60) | FFAR1LMNACYP1A2HIF1ARAB9A | |
| SCHEMBL13824200 | 0.73 | HTT (0.51) | LMNASMN1; SMN2CDK1CCNB1CCNA2 | |
| SCHEMBL6624366 | 0.71 | HDAC3 (0.43) | LMNACYP1A2RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0465879-A1 | Derivatives of 4-(2,4-difluoro-biphenylyl)-2-methyl-4-oxo-butanoic acid | VYZKUMNY USTAV PRO FARMACII A BIOCHEMII STATNI PODNIK (CS) | 1992-01-15 | — | — | EP | disclosed |