SCHEMBL9617618

SCHEMBL9617618

C=CCCC/C=C/COC(=O)C(=C)C

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
TSHR P16473 3/20 0.43
MAPT P10636 4/20 0.42
LMNA P02545 2/20 0.42
USP2 O75604 2/20 0.42
CYP3A4 P08684 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
RECQL P46063 1/20 0.42
THRB P10828 1/20 0.37
HPGD P15428 1/20 0.35
CNR1 P21554 1/20 0.33
ABCC4 O15439 1/20 0.32
FAAH O00519 2/20 0.32
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9617619 1.00 ALDH1A1 (0.44) ALDH1A1TSHRMAPTLMNAUSP2
SCHEMBL20577622 0.91 TSHR (0.51) ALDH1A1TSHRMAPTLMNAUSP2
SCHEMBL354283 0.86 THRB (0.50) ALDH1A1TSHRMAPTLMNAUSP2
SCHEMBL356434 0.86 THRB (0.50) ALDH1A1TSHRMAPTLMNAUSP2
SCHEMBL27733968 0.84 TSHR (0.53) ALDH1A1TSHRMAPTLMNAUSP2
SCHEMBL991225 0.84 MAPT (0.53) ALDH1A1TSHRMAPTLMNAUSP2
SCHEMBL991224 0.84 MAPT (0.53) ALDH1A1TSHRMAPTLMNAUSP2
SCHEMBL5654625 0.83 TSHR (0.52) ALDH1A1TSHRLMNATHRBPOLB
SCHEMBL1636583 0.83 TSHR (0.52) ALDH1A1TSHRLMNATHRBPOLB
SCHEMBL1636584 0.83 TSHR (0.52) ALDH1A1TSHRLMNATHRBPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4049266-A None JP disclosed
US-11084893-B2 Ethylene-based polymers and processes for the same DOW GLOBAL TECHNOLOGIES LLC (US) 2021-08-10 US disclosed
US-11084893-B2 Ethylene-based polymers and processes for the same DOW GLOBAL TECHNOLOGIES LLC (US) 2021-08-10 US disclosed
EP-3630853-B1 ETHYLENE-BASED POLYMERS AND PROCESSES FOR THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2021-03-17 EP disclosed
EP-3630853-B1 ETHYLENE-BASED POLYMERS AND PROCESSES FOR THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2021-03-17 EP disclosed
US-20200148799-A1 ETHYLENE-BASED POLYMERS AND PROCESSES FOR THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2020-05-14 US disclosed
US-20200148799-A1 ETHYLENE-BASED POLYMERS AND PROCESSES FOR THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2020-05-14 US disclosed
JP-H0449266-A (METH)ACRYLIC ESTER AND ITS PRODUCTION KURARAY CO LTD 1992-02-18 JP disclosed