Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | RARB | P10826 | 3/20 | 0.39 |
| ▸ | RARG | P13631 | 3/20 | 0.39 |
| ▸ | RARA | P10276 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5657117 | 0.80 | NOTUM (0.45) | PTGS1PTGS2NOTUMRARBRARG | |
| SCHEMBL5656647 | 0.79 | NOTUM (0.44) | PTGS1PTGS2NOTUMRARBRARG | |
| SCHEMBL5656855 | 0.79 | RARB (0.45) | PTGS1PTGS2NOTUMRARBRARG | |
| SCHEMBL5654523 | 0.77 | NOTUM (0.42) | PTGS1PTGS2NOTUMRARBRARG | |
| SCHEMBL9617566 | 0.75 | GAA (0.47) | PTGS1PTGS2NOTUMRARBRARG | |
| Benfuresate SCHEMBL54959 | 0.74 | PTGS1 (0.41) | PTGS1PTGS2NOTUMRARBRARG | |
| Benfuresate SCHEMBL29396663 | 0.74 | PTGS1 (0.41) | PTGS1PTGS2NOTUMRARBRARG | |
| Benfuresate SCHEMBL4890261 | 0.74 | PTGS1 (0.41) | PTGS1PTGS2NOTUMRARBRARG | |
| SCHEMBL29104730 | 0.74 | APP (0.36) | RXRAHTT | |
| SCHEMBL11449845 | 0.73 | ALDH1A1 (0.46) | MAPTCA12CA2SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4046168-A | — | — | None | — | — | JP | disclosed |
| JP-H0446168-A | NEW BENZOFURAN DERIVATIVE AND HERBICIDE CONTAINING SAME DERIVATIVE | MITSUBISHI PETROCHEM CO LTD | 1992-02-17 | — | — | JP | disclosed |